Pipeline & Platform
Pearl Therapeutics is rapidly developing a portfolio of products that offer distinct clinical benefits to patients in the most widely used inhaled drug delivery format, the metered dose inhaler (MDI). Our hydrofluoroalkane (HFA) MDI-based products use proprietary engineered particle technology to achieve unprecedented performance and reliability from an MDI, and are intended to treat patients at all stages of chronic obstructive pulmonary disease (COPD) and asthma. Pearl has successfully formulated a majority of the bronchodilators and inhaled steroids commonly used in the respiratory space, along with their combinations, thereby demonstrating the versatility of its platform. The company is focused on developing high value combination products for patients across all stages of disease, with our lead product a twice-daily bronchodilator LAMA/LABA combination for the treatment of COPD.
Pipeline
Combination Therapy: Glycopyrrolate and Formoterol Inhalation Aerosol for COPD
Unique long-acting muscarinic antagonist (LAMA)+ long acting ß2-agonist (LABA) combination product
Combination Therapy: Inhaled Corticosteroid (ICS)+LABA+LAMA Inhalation Aerosol
Delivery of three therapies in one inhalation
Monotherapy: Glycopyrrolate Inhalation Aerosol for COPD
LAMA bronchodilator
Monotherapy: Formoterol Inhilation Aerosol for COPD
LABA bronchodilator
Combination therapy: ICS+LABA Inhalation Aerosol
Delivery of two therapies in one inhalation, with compelling product advantages